Items where Author is "Tham, Chau Ling"

Abd Rahman, Noor Izzah and Tham, Chau Ling and Abd Hamid, Roslida (2024) Inhibition of angiogenesis and metastasis in colorectal cancer cell lines through KRAS-associated signaling pathways by 2-methoxy-6-undecyl-1,4-benzoquinone. Chemico-Biological Interactions, 399. art. no. 111151. ISSN 0009-2797; eISSN: 1872-7786

Mohd Kasim, Vivi Nur Khalieda and Lee, Yu Zhao and Bakrin, Ikmal Hisyam and Hussain, Mohd Khairi and Ahmad Israf, Daud and Shaari, Khozirah and Tan, Ji Wei and Lee, Ming Tatt and Tham, Chau Ling (2024) Oral and topical administration of a geranyl acetophenone attenuates DNCB‑induced atopic dermatitis‑like skin lesions in BALB/c mice. Scientific Reports, 14 (1). art. no. 17623. pp. 1-13. ISSN 2045-2322

Wong, Pei Lou and Zolkeflee, Nur Khaleeda Zulaikha and Ramli, Nurul Shazini and Tan, Chin Ping and Azlan, Azrina and Tham, Chau Ling and Shaari, Khozirah and Abas, Faridah (2024) Antidiabetic effect of Ardisia elliptica extract and its mechanisms of action in STZ-NA-induced diabetic rat model via 1H-NMR-based metabolomics. Journal of Ethnopharmacology, 318 (pt.B). art. no. 117015. pp. 1-13. ISSN 0378-8741; ESSN: 1872-7573

Zolkeflee, Nur Khaleeda Zulaikha and Wong, Pei Lou and Maulidiani, M. and Ramli, Nurul Shazini and Azlan, Azrina and Mediani, Ahmed and Tham, Chau Ling and Abas, Faridah (2024) Revealing metabolic and biochemical variations via 1H NMR metabolomics in streptozotocin-nicotinamide-induced diabetic rats treated with metformin. Biochemical and Biophysical Research Communications, 708. art. no. 149778. ISSN 0006-291X

Kow, Audrey Siew Foong and Khoo, Leng Wei and Tan, Ji Wei and Abas, Faridah and Lee, Ming-Tatt and Ahmad Israf, Daud and Shaari, Khozirah and Tham, Chau Ling (2023) Clinacanthus nutans aqueous extract exerts anti-allergic activity in preclinical anaphylactic models via alternative IgG pathway. Journal of Ethnopharmacology, 303 (116003). ISSN 0378-8741; ESSN: 1872-7573

Yu, Chai Xin and Tan, Jian Wei and Rullah, Kamal and Imran, Syahrul and Tham, Chau Ling (2023) Insight parameter drug design for human β-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of α-keto-[1,2,4]-oxadiazoles. Journal of Biomolecular Structure and Dynamics, 41 (22). pp. 12978-12996. ISSN 0739-1102; ESSN: 1538-0254

Yu, Chai Xin and Tan, Jian Wei and Rullah, Kamal and Imran, Syahrul and Tham, Chau Ling (2023) Insight parameter drug design for human β-tryptase inhibition integrated molecular docking, QSAR, molecular dynamics simulation, and pharmacophore modelling studies of α-keto-[1,2,4]-oxadiazoles. Journal of Biomolecular Structure and Dynamics, 41 (22). pp. 12978-12996. ISSN 0739-1102; ESSN: 1538-0254

Mohd Kasim, Vivi Nur Khalieda and Noble, Siti Mahirah and Liew, Kong Yen and Tan, Ji Wei and Israf, Daud Ahmad and Tham, Chau Ling (2022) Management of atopic dermatitis via oral and topical administration of herbs in murine model: a systematic review. Frontiers in Pharmacology, 13. art. no. 785782. pp. 1-17. ISSN 1663-9812

Wong, Carisa Su-Ann and Lim, Cheng Wei and Mohammed, Haruna Isa and Liew, Kong Yen and Tham, Chau Ling and Tan, Ji Wei and Chee, Hui Yee (2022) Current perspective of plant-based diets on communicable diseases caused by viruses: a mini review. Frontiers in Nutrition, 9. art. no. 786972. pp. 1-8. ISSN 2296-861X

Liew, Kong Yen and Koh, Sue Kie and Hooi, Suet Li and Ng, Matthew Kah Lup and Chee, Hui-Yee and Harith, Hanis Hazeera and Israf, Daud Ahmad and Tham, Chau Ling (2022) Rhinovirus-induced cytokine alterations with potential implications in asthma exacerbations: a systematic review and meta-analysis. Frontiers in Immunology, 13. 1- 18. ISSN 1664-3224

Chen, Li and Jiang, Xudong and Gao, Si and Liu, Xueping and Gao, Ying and Siew, Audrey Foong Kow and Tham, Chau Ling and Ming, Tatt Lee (2022) Sensitization effect of kaempferol from persimmon leaves on HepG2 hepatoma cells with ABT-199 resistance and its molecular mechanisms. Frontiers in Pharmacology, 13. art. no. 1032069. pp. 1-15. ISSN 1663-9812

Chan, Yee Han and Liew, Kong Yen and Tan, Ji Wei and Shaari, Khozirah and Israf, Daud Ahmad and Tham, Chau Ling (2021) Pharmacological properties of 2,4,6-Trihydroxy-3-geranyl acetophenone and the underlying signaling pathways: progress and prospects. Frontiers in Pharmacology, 12. art. no. 736339. pp. 1-11. ISSN 1663-9812

Yong, Poi Yi Aw and Islam, Fahmida and Harith, Hanis Hazeera and Israf, Daud Ahmad and Tan, Ji Wei and Tham, Chau Ling (2021) The potential use of honey as a remedy for allergic diseases: a mini review. Frontiers in Pharmacology, 11. art. no. 599080. pp. 1-11. ISSN 1663-9812

Ong, Chun Hao and Tham, Chau Ling and Harith, Hanis Hazeera and Firdaus, Nazmi and Israf, Daud Ahmad (2021) TGF-β-induced fibrosis: a review on the underlying mechanism and potential therapeutic strategies. European Journal of Pharmacology, 911. art. no. 174510. pp. 1-16. ISSN 0014-2999; ESSN: 1879-0712

Tham, Chau Ling and Sin, Yee Yeoh and Ong, Chun Hao and Harith, Hanis Hazeera and Israf Ali, Daud Ahmad (2021) A synthetic curcuminoid analogue, 2,6-Bis-4-(Hydroxyl-3-Methoxybenzylidine)-Cyclohexanone (BHMC) ameliorates acute airway inflammation of allergic asthma in ovalbumin-sensitized mice. Mediators of Inflammation, 2021. pp. 1-10. ISSN 0962-9351; ESSN: 1466-1861

Mohd Narawi, Masturah and Hock, Ing Chiu and Yong, Yoke Keong and Mohamad Zain, Nur Nadhirah and Ramachandran, Muggundha Raoov and Tham, Chau Ling and Samsurrijal, Siti Fatimah and Lim, Vuanghao (2020) Biocompatible nutmeg oil-loaded nanoemulsion as phyto-repellent. Frontiers in Pharmacology, 11. art. no. 214. pp. 1-15. ISSN 1663-9812

Kow, Audrey Siew Foong and Fong, Lai Yen and Khoo, Leng Wei and Tan, Ji Wei and Lee, Ming Tatt and Israf Ali, Daud Ahmad and Abas, Faridah and Shaari, Khozirah and Tham, Chau Ling (2020) Clinacanthus nutans aqueous extract suppresses the release of histamine and β-Hexosaminidase inin-vitro model of IgE-mediated mast cell degranulation. Pharmacognosy Magazine, 16 (69). 400 - 408. ISSN 0973-1296; ESSN: 0976-4062

Chan, Yee Han and Harith, Hanis Hazeera and Israf Ali, Daud Ahmad and Tham, Chau Ling (2020) Differential regulation of LPS-mediated VE-cadherin disruption in human endothelial cells and the underlying signaling pathways: a mini review. Frontiers in Cell and Developmental Biology, 7. pp. 1-10. ISSN 2296-634X

Ismail, Norazren and Jambari, Nuzul Noorahya and Tham, Chau Ling and Harith, Hanis Hazeera and Shaari, Khozirah and Israf Ali, Daud Ahmad (2019) 2,4,6,-trihydroxy-3-geranylacetophenone (tHGA) suppresses chronic allergic airway inflammation in ovalbumin-sensitized mice via intraperitoneal route. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 2-9. ISSN 1675-8544; ESSN: 2636-9346

Yap, Hui Min and Israf Ali, Daud Ahmad and Harith, Hanis Hazeera and Tham, Chau Ling and Sulaiman, Mohd Roslan (2019) Crosstalk between signaling pathways involved in the regulation of airway smooth muscle cell hyperplasia. Frontiers in Pharmacology, 10. art. no. 1148. pp. 1-16. ISSN 1663-9812

Liew, Kong Yen and Rosly, Nur A'dilah and Abas, Faridah and Leong, Sze Wei and Israf Ali, Daud Ahmad and Tham, Chau Ling (2019) Effect of diarylpentanoid analogues on lipopolysaccharide-induced interleukin-6 and interleukin-8 gene expression in airway inflammation. Malaysian Journal of Medicine and Health Sciences, 15 (SP2). pp. 10-17. ISSN 1675-8544; ESSN: 2636-9346

Soo, Kuan Meng and Tham, Chau Ling and Khalid, Bahariah and Basir, Rusliza and Chee, Hui Yee (2019) IL-8 as a potential in-vitro severity biomarker for dengue disease. Tropical Biomedicine, 36 (4). pp. 1027-1037. ISSN 0127-5720

Tan, Ji Wei and Wan Zahidi, Nuha Fahimah and Siew, Audrey Foong Kow and Soo, Kuan Meng and Shaari, Khozirah and Ahmad Israf, Daud and Chee, Hui Yee and Tham, Chau Ling (2019) Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells. Bioscience Reports, 39 (6). pp. 1-10. ISSN 0144-8463; ESSN: 1573-4935

Tham, Chau Ling and Kow, Audrey Siew Foong and Wan Zahidi, Nuha Fatimah (2018) Association of immunoglobulin G abnormalities in diseases: a mini review. Life Sciences, Medicine and Biomedicine, 2 (1). pp. 1-6. ISSN 2251-9939

Leng, Wei Khoo and Siew, Audrey Foong Kow and M., Maulidiani and Lee, Ming Tatt and Tan, Chin Ping and Shaari, Khozirah and Tham, Chau Ling and Abas, Faridah (2018) Hematological, biochemical, histopathological and 1H-NMR metabolomics application in acute toxicity evaluation of clinacanthus nutans water leaf extract. Molecules, 23 (9). art. no. 2172. pp. 1-18. ISSN 1420-3049

Abdul Hamid, Nur Ashikin and Maulidiani, Maulidiani and Mediani, Ahmed and Yahya, Ummul Izzatul Izzah and Ismail, Intan Safinar and Tham, Chau Ling and Shadid, Khalid and Abas, Faridah (2018) Physicochemical characteristics, nutritional composition, and phytochemical profiles of nine Algerian date palm fruit (Phoenix dactylifera L.) varieties. Journal of Food Biochemistry, 42 (6). art. no. 12663. pp. 1-13. ISSN 0145-8884

Khoo, Leng Wei and Kow, Audrey Siew Foong and Maulidiani, Maulidiani and Lee, Ming Tatt and Tan, Chin Ping and Shaari, Khozirah and Tham, Chau Ling and Abas, Faridah (2018) Plasma and urine metabolite profiling reveals the protective effect of Clinacanthus nutans in an ovalbumin-induced anaphylaxis model: ¹H-NMR metabolomics approach. Journal of Pharmaceutical and Biomedical Analysis, 158. 438 - 450. ISSN 0731-7085; ESSN: 1873-264X

Yap, Hui Min and Lee, Yu Zhao and Harith, Hanis Hazeera and Tham, Chau Ling and Cheema, Manraj Singh and Shaari, Khozirah and Israf Ali, Daud Ahmad (2018) The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation. Scientific Reports, 8. art. no. 16640. Jan-14. ISSN 2045-2322

Tee, Yee Sim and Harith, Hanis Hazeera and Tham, Chau Ling and Md Hashim, Nur Fariesha and Shaari, Khozirah and Sulaiman, Mohd Roslan and Israf Ali, Daud Ahmad (2018) The protective effects of a synthetic geranyl acetophenone in a cellular model of TNF-α-induced pulmonary epithelial barrier dysfunction. Molecules, 23 (6). art. no. 1355. pp. 1-20. ISSN 1420-3049; ESSN: 1420-3049

Tan, Ji Wei and Israf, Daud Ahmad and Md Hashim, Nur Fariesha and Cheah, Yoke Kqueen and Harith, Hanis Hazeera and Shaari, Khozirah and Tham, Chau Ling (2017) LAT is essential for the mast cell stabilising effect of tHGA in IgE-mediated mast cell activation. Biochemical Pharmacology, 144. 132 - 148. ISSN 0006-2952; ESSN: 1873-2968

Tan, Ji Wei and Israf Ali, Daud Ahmad and Harith, Hanis Hazeera and Md Hashim, Nur Fariesha and Ng, Chean Hui and Shaari, Khozirah and Tham, Chau Ling (2017) Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis. Toxicology and Applied Pharmacology, 319. pp. 47-58. ISSN 0041-008X; ESSN: 1096-0333

Lee, Yu Zhao and Yap, Hui Min and Shaari, Khozirah and Tham, Chau Ling and Sulaiman, Mohd Roslan and Israf Ali, Daud Ahmad (2017) Blockade of eosinophil-induced bronchial epithelial-mesenchymal transition with a geranyl acetophenone in a coculture model. Frontiers in Pharmacology, 8. pp. 1-13. ISSN ESSN: 1663-9812

Harasstani, Omar A. and Tham, Chau Ling and Israf Ali, Daud Ahmad (2017) Kaempferol and chrysin synergies to improve septic mice survival. Molecules, 22 (1). pp. 1-13. ISSN 1420-3049

Soo, Kuan Meng and Khalid, Bahariah and Ching, Siew Mooi and Tham, Chau Ling and Basir, Rusliza and Chee, Hui Yee (2017) Meta-analysis of biomarkers for severe dengue infections. PeerJ, 2017 (9). pp. 1-25. ISSN 2167-8359

Chong, Yi Joong and Musa, Muhammad Nazmi Firdaus and Ng, Chean Hui and Shaari, Khozirah and Israf Ali, Daud Ahmad and Tham, Chau Ling (2016) Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells. Journal of Ethnopharmacology, 192. pp. 248-255. ISSN 0378-8741; ESSN: 1872-7573

Tan, Ji Wei and Israf Ali, Daud Ahmad and Shaari, Khozirah and Tham, Chau Ling (2015) 2, 4, 6,-trihydroxy- 3-geranylacetophenone (tHGA) inhibits newly synthesized mediators release in IgE-mediated mast cell degranulation. Malaysian Journal of Microscopy, 11 (Supp 1). pp. 37-38. ISSN 1823-7010

Rajajendram, Revathee and Tham, Chau Ling and Akhtar, Mohamad Nadeem and Sulaiman, Mohd Roslan and Israf Ali, Daud Ahmad (2015) Inhibition of epithelial CC-family chemokine synthesis by the synthetic chalcone DMPF-1 via disruption of NF-κB nuclear translocation and suppression of experimental asthma in mice. Mediators of Inflammation, 2015. art. no. 176926. pp. 1-14. ISSN 0962-9351; ESSN: 1466-1861

Chong, Yi Joong and Israf Ali, Daud Ahmad and Shaari, Khozirah and Tham, Chau Ling (2015) A phloroglucinol from Melicope ptelefolia preserves barrier integrity of lipopolysaccharide-induced endothelial cells: study on junctional proteins and cytoskeleton remodeling. Malaysian Journal of Microscopy, 11 (Supp 1). p. 21. ISSN 1823-7010

Leong, Sze Wei and Mohd Faudzi, Siti Munirah and Abas, Faridah and Mohd Aluwi, Mohd Fadhlizil Fasihi and Rullah, Kamal and Lam, Kok Wai and Abdul Bahari, Mohd Nazri and Ahmad, Syahida and Tham, Chau Ling and Shaari, Khozirah and Lajis, Md. Nordin (2014) Synthesis and SAR study of diarylpentanoid analogues as new anti-inflammatory agents. Molecules, 19 (10). pp. 16058-16081. ISSN 1420-3049

Tan, Ji Wei and Tham, Chau Ling and Israf Ali, Daud Ahmad and Lee, Sang Hyub and Kim, Min Kyu (2013) Neuroprotective effects of biochanin A against glutamate-induced cytotoxicity in PC12 cells via apoptosis inhibition. Neurochemical Research, 38 (3). pp. 512-518. ISSN 0364-3190; ESSN: 1573-6903

Tan, Ji Wei and Tham, Chau Ling and Ahmad Israf, Daud and Lee, Sang Hyub and Kim, Min Kyu (2013) Neuroprotective effects of biochanin A against glutamate-induced cytotoxicity in PC12 cells via apoptosis inhibition. Neurochemical Research, 38 (3). pp. 512-518. ISSN 0364-3190; ESSN: 1573-6903

Lee, Yu Zhao and Lee, Ming Tatt and Lajis, Nordin and Sulaiman, Mohd Roslan and Israf Ali, Daud Ahmad and Tham, Chau Ling (2012) Development and validation of a bioanalytical method for quantification of 2,6-bis-(4-hydroxy-3-methoxybenzylidene)-cyclohexanone (BHMC) in rat plasma. Molecules, 17 (12). pp. 14555-14564. ISSN 1420-3049

Harasstani, Omar A. and Moin, Saidi and Tham, Chau Ling and Liew, Choi Yi and Ismail, Norazren A. and Rajajendram, Revathee and Harith, Hanis Hazeera and Zakaria, Zainul Amiruddin and Tengku Mohamad, Tengku Azam Shah and Sulaiman, Mohd Roslan and Israf Ali, Daud Ahmad (2010) Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells. Inflammation Research, 59 (9). pp. 711-721. ISSN 1023-3830, ESSN: 1420-908X

Liew, Choi Yi and Tham, Chau Ling and Lam, Kok Wai and Tengku Mohamad, Tengku Azam Shah and Kim, Min Kyu and Cheah, Yoke Kqueen and Zakaria, Zainul Amiruddin and Sulaiman, Mohd Roslan and Lajis, Md Nordin and Israf Ali, Daud Ahmad (2010) A synthetic hydroxypropenone inhibits nitric oxide, prostaglandin E2, and proinflammatory cytokine synthesis. Immunopharmacology and Immunotoxicology, 32 (3). pp. 495-509. ISSN 0892-3973; ESSN: 1532-2513

Israf Ali, Daud Ahmad and Tham, Chau Ling and Ahmad, Syahida and Lajis, Md. Nordin and Sulaiman, Mohd Roslan and Mohamad, Azam Shah and Zakaria, Zainul Amiruddin (2010) Atrovirinone inhibits proinflammatory mediator synthesis through disruption of NF-kappaB nuclear translocation and MAPK phosphorylation in the murine monocytic macrophage RAW 264.7. Phytomedicine, 17 (10). pp. 732-739. ISSN 0944-7113; ESSN: 1618-095X

Tham, Chau Ling and Liew, Choi Yi and Lam, Kok Wai and Tengku Mohamad, Tengku Azam Shah and Kim, Min Kyu and Cheah, Yoke Kqueen and Zakaria, Zainul Amiruddin and Sulaiman, Mohd Roslan and Lajis, Nordin and Israf Ali, Daud Ahmad (2010) A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis. European Journal of Pharmacology, 628 (1-3). pp. 247-254. ISSN 0014-2999; ESSN: 1879-0712

Kow, Audrey and Khoo, Leng Wei and Lee, Ming Tatt and Daud, Ahmad Israf and Abas, Faridah and Tham, Chau Ling (2016) Anti-allergic effect of Clinacanthus nutans aqueous extract: protection against IgE-mediated passive systemic anaphylaxis. In: 6th Asia-Pacific Pharma Congress, 11-13 July 2016, Kuala Lumpur, Malaysia. .

Tan, Ji Wei and Daud, Ahmad Israf and Shaari, Khozirah and Tham, Chau Ling (2016) Oral administration of a potential mast cell stabilizer, tHGA, prevents IgE-mediated anaphylaxis in rats. In: Joint Congress of Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI) and Asia Pacific Association of Pediatric Allergy, Respirology and Immunology (APAPARI) 2016. The Era of Allergy: Local and Global Insights and Intervention, 17-20 October 2016, Kuala Lumpur. (p. 68).

Tham, Chau Ling (2016) A phloroglucinol from Melicope ptelefolia attenuates IgE-mediated mast cell degranulation via calcium-dependent signalling pathways. In: 16th International Congress of Immunology (ICI 2016), 21-26 Aug. 2016, Melbourne, Australia. .

Che Ku Daud, Che Ku Dahlan and Zailani, Muhamad Zulhilmi and Sukiman, Nor Erma Suryana and Tham, Chau Ling and Ahmad, Zuraini and Yong, Yoke Keong and Mohd Zain, Zetty Nadia and Abdullah, Muhammad Nazrul Hakim (2014) Cytotoxicity effect of 6-mercaptopurine and 6-mercaptopurine riboside on RAW 264.7 and HIG-82 cell lines. In: Malaysia International Biological Symposium 2014, 28-29 Oct. 2014, Putrajaya, Malaysia. (pp. 303-308).

Daud Ahmad Israf Ali (2012) Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders. PI2012003491.