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Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders


Citation

Daud Ahmad Israf Ali (2012) Use of the curcumin analog BHMC in the treatment of endothelial dysfunction and related disorders. PI2012003491.

Abstract / Synopsis

The present invention relates to an analog of curcumin, 2,6-bis-(4-hydroxyl-3-methoxybenzylidine)cyclohexanone (BHMC) or a pharmaceutically acceptable salt, solvate or derivative thereof, for use in treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction. Furthermore provided are methods of treating, preventing or managing endothelial dysfunction and/or a disorder associated with endothelial dysfunction using BHMC or a pharmaceutically acceptable salt, solvate or derivative thereof. The invention provides also a method for attenuating endothelial dysfunction in an endothelial cell and/or attenuating the hallmarks of endothelial dysfunction in an endothelial cell.


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Additional Metadata

Item Type: Patent
Application Number: PI2012003491
Filing Date: 2012-08-02
Divisions: Faculty of Veterinary Medicine
Keywords: Curcumin analog; BHMC; Pharmaceutically acceptable salt; Endothelial dysfunction
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 05 Feb 2015 12:21
Last Modified: 05 Feb 2015 12:21
URI: http://psasir.upm.edu.my/id/eprint/33360
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