Citation
Nordin, Abdul Jalil and Abdul Rahim, Noraini and Rossetti, Claudio and Lind, Peter and Kresnik, Ewald
(2009)
Whole body imaging using 18-Fluorine Fluorodeoxyglucose
(18F-FDG) Positron Emission Tomography/Computed
Tomography (PET/CT) with or without contrast enhanced
computed tomography (CT) in dignosing arteritis.
Malaysian Journal of Medicine and Health Sciences, 5 (1).
pp. 59-67.
ISSN 1675-8544
Abstract
Introduction: Takayasu’s Arteritis and Horton’s Arteritis are two rare cases of autoimmune
complex diseases resulting in sterile inflammatory reactions affecting the wall of
large and medium sized arteries. Various radiological and interventional methods employed
are inconclusive and become diagnostic only when complications begin to set in. The new
non-invasive hybrid Positron Emission Tomography Computed Tomography (PET/CT)
using 18Florine-Fluorodeoxyglucose (18F-FDG) imaging technique could detect arteritis in
an early clinical stage when routine conventional cross-sectional imaging was inconclusive.
Method: Two cases from Klagenfurt Hospital, Austria and Milan General Hospital, Italy
were compared with image acquisition being done in the respective hospitals. In Klagenfurt,
PET/CT image acquisition was performed using intravenous contrast administration and in
Milan, CT parameters were used as attenuation correction and anatomical correlation of
PET images. Results: CT performed using both methods, with or without iodinated
contrast media, were useful in detecting arteritis. Conclusion: It is concluded that PET/
CT aside from being a useful tool in cancer imaging, is also useful for pyrexia of unknown
origin. PET/CT should be employed early in managing this clinical condition where arteritis
is a possible diagnosis.
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