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Quantifying myelin in neonates using magnetic resonance imaging: a systematic literature review


Citation

Arshad, Nabila Hanem and Abu Hassan, Hasyma and Omar, Nur Farhayu and Zainudin, Zurina (2023) Quantifying myelin in neonates using magnetic resonance imaging: a systematic literature review. Clinical and Experimental Pediatrics, 67 (8). pp. 371-385. ISSN 2713-4148

Abstract

This review aimed to assess the usefulness of various magnetic resonance imaging (MRI) techniques for the quantification of neonatal white matter myelination. The Scopus, PubMed, and Web of Science databases were searched to identify studies following the PRISMA (preferred reporting items for systematic reviews and metaanalyses) statement using quantitative MRI techniques to examine samples collected from neonates to quantify myelin.Twelve studieswereultimately included.The results demonstrated that in validation studies, relaxometry is the most frequently explored approach (83.33%), followed by magnetization transfer imaging (8.33%) and a new automatic segmentation technique (8.33%). Synthetic MRI is recommended for quantifying myelin in neonates because of several advantages that outweigh a few negligible limitations.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Hospital Pengajar UPM
DOI Number: https://doi.org/10.3345/cep.2023.00514
Publisher: Korean Pediatric Society
Keywords: Brain; Magnetic resonance imaging; Myelin; Neonate; Quantitative
Depositing User: Ms. Nur Faseha Mohd Kadim
Date Deposited: 10 Jul 2025 03:06
Last Modified: 10 Jul 2025 03:06
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3345/cep.2023.00514
URI: http://psasir.upm.edu.my/id/eprint/118425
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