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An overview of the potential therapeutic applications of essential oils


Citation

Nasser Aljaafari, Mariam and AlAli, Asma Obaid and Baqais, Laila and Alqubaisy, Maream and AlAli, Mudhi and Molouki, Aidin and Abdullah, Janna Ong and Abushelaibi, Aisha and Lai, Kok-Song and Lim, Swee Hua Erin (2021) An overview of the potential therapeutic applications of essential oils. Molecules, 26 (3). art. no. 628. pp. 1-27. ISSN 1420-3049

Abstract

The emergence of antimicrobial resistance (AMR) has urged researchers to explore therapeutic alternatives, one of which includes the use of natural plant products such as essential oils (EO). In fact, EO obtained from clove, oregano, thymus, cinnamon bark, rosemary, eucalyptus, and lavender have been shown to present significant inhibitory effects on bacteria, fungi, and viruses; many studies have been done to measure EO efficacy against microorganisms. The strategy of combinatory effects via conventional and non-conventional methods revealed that the combined effects of EO-EO or EO-antibiotic exhibit enhanced efficacy. This paper aims to review the antimicrobial effects of EO, modes of EO action (membrane disruption, efflux inhibition, increase membrane permeability, and decrease in intracellular ATP), and their compounds' potential as effective agents against bacteria, fungi, and viruses. It is hoped that the integration of EO applications in this work can be used to consider EO for future clinical applications.


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Official URL or Download Paper: https://www.mdpi.com/1420-3049/26/3/628

Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.3390/molecules26030628
Publisher: Multidisciplinary Digital Publishing Institute
Keywords: Essential oils; Antimicrobial activity; Oregano; Thymol; Carvacrol; Cinnamon bark; Synergistic activity; Genomics; Proteomics
Depositing User: Ms. Nuraida Ibrahim
Date Deposited: 22 Mar 2023 08:18
Last Modified: 22 Mar 2023 08:18
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules26030628
URI: http://psasir.upm.edu.my/id/eprint/95881
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