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Search for New Antioxidants and Other Related Bioactive Compounds from Zingiberaceous Species


Citation

Mohamad, Habsah (2002) Search for New Antioxidants and Other Related Bioactive Compounds from Zingiberaceous Species. PhD thesis, Universiti Putra Malaysia.

Abstract / Synopsis

Thirty-one species from Zingiberacea family were screened for their antioxidant (FTC method), antimicrobial (disc diffusion method), and antitumour promoting (EBV EA assay method) activities. Three species, A lpinia zerumbet, A lpinia rfflesiana and Etlingera elatiar, were selected for further study, based on their promising preliminary biological activities. Five known compounds were isolatpd hom the rhizomes of Alpinia zerumbet, namely S,6-dehydrokawain, flavokawin B, l,7-diphenyl-Shydroxy- 6-heptene-3-one, (-)-pinocembrin, and a mixture of stigmasterol and β-sitosterol. From the fruits of Alpinia raffiesiana, seven compounds were isolated, namely 5,6-dehydrokawain: flavokawin B, l,7-diphenyl-5- hydroxy-6-heptene-3-one, (-)-pinocembrin, cardamonin, (-)-pinostrobin, and 2',3',4',6' -tetrahydroxychalcone. This is the first report on the isolation of 2',3',4',6' -tetrahydroxychalcone from Alpinia.


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Additional Metadata

Item Type: Thesis (PhD)
Subject: Zingiberaceae
Subject: Antioxidants
Subject: Bioactive compounds
Call Number: FSAS 2002 55
Chairman Supervisor: Associate Professor Dr. Md. Nordin Hj. Lajis, PhD
Divisions: Faculty of Environmental Studies
Depositing User: Muizzudin Kaspol
Date Deposited: 14 Feb 2011 01:35
Last Modified: 29 Oct 2012 01:06
URI: http://psasir.upm.edu.my/id/eprint/9525
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