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Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation


Citation

Muhamad Damanhuri, Fatimahtuz Zahrah and Aun, Evelyn and Arushothy, Revathy and Kandasamy, Thenmalar and Zaini, Adillahtul Bushro and Zakariah, Siti Zulaikha and Masri, Siti Norbaya (2021) Serotype 15C streptococcus pneumoniae with third cranial nerve palsy: unusual serotype and presentation. Malaysian Journal of Medicine and Health Sciences, 17 (4). 442 - 444. ISSN 1675-8544; ESSN: 2636-9346

Abstract

We present a unique case of pneumococcal meningitis caused by serotype 15C, a non-vaccine serotype, which islong thought to be non-virulent. Our patient is a young lady with a known case of plaque psoriasis, presented with sudden onset of left oculomotor nerve palsy and severe headache two days prior to admission. The clinical features were initially mimicking of brain tumour and brain aneurysm. The diagnosis of pneumococcal meningitis was confirmed by the bacterial antigen test and genome detection using multiplex PCR from the CSF. The blood culture also grew Streptococcus pneumoniae. Serotyping was performed on the isolate using Neufeld's Quellung method and it was identified as serotype 15C. Psoriatic skin disease was identified as a potential source of this invasive infection.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Universiti Putra Malaysia
Keywords: Invasive pneumococcal disease; Meningitis; Serotype 15C; Streptococcus pneumoniae
Depositing User: Ms. Che Wa Zakaria
Date Deposited: 12 Apr 2023 01:32
Last Modified: 12 Apr 2023 01:32
URI: http://psasir.upm.edu.my/id/eprint/95051
Statistic Details: View Download Statistic

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