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Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child?


Citation

Kandasamy, Thenmalar and Muhamad Damanhuri, Fatimahtuz Zahrah and Zaini, Adillahtul Bushro and Zakariah, Siti Zulaikha and Ibrahim, Rosni (2021) Adult diphteria: possible transmission of Corynebacterium diphtheriae from unvaccinated child? Malaysian Journal of Medicine and Health Sciences, 17 (3). pp. 311-314. ISSN 1675-8544; ESSN: 2636-9346

Abstract

A case of a toxigenic strain of Corynebacterium diphtheriae in an immunocompetent adult is presented, with the possibility of the adult acquiring the infection from her unvaccinated child. The abovementioned adult is a 29-year-old housewife who was previously immunised with diphtheria, tetanus, and pertussis (DTaP) vaccination in childhood, who presented fever, cough, sore throat, hoarseness of voice, odynophagia, and bilaterally enlarged tonsils. A throat swab confirmed the presence of toxigenic Corynebacterium diphtheriae. The patient was given 80,000 international units (IU) dose of diphtheria antitoxin (DAT) and treated with 2.4 million units (MU) QID intravenous penicillin and oral erythromycin 800 mg twice daily for two weeks. The patient responded well to the treatment and recovered with no cardiovascular or neurotoxicity.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Corynebacterium diphtheriae; Diphtheria, Tetanus and pertussis (DTaP); Elek test; Diphtheria antitoxin
Depositing User: Mohamad Jefri Mohamed Fauzi
Date Deposited: 10 Sep 2021 01:43
Last Modified: 10 Sep 2021 01:43
URI: http://psasir.upm.edu.my/id/eprint/90400
Statistic Details: View Download Statistic

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