Citation
Ibiyeye, Kehinde Muibat and Banke, Idris Sherifat and Zakaria, Md Zuki Abu Bakar
(2020)
Cockle shell‑derived aragonite calcium carbonate nanoparticle for targeting cancer and breast cancer stem cells.
Cancer Nanotechnology, 11.
art. no. 10.
pp. 1-15.
ISSN 1868-6958; ESSN: 1868-6966
Abstract
Cockle shell-derived aragonite calcium carbonate nanoparticles (CACNP) have demonstrated prospect as nano-sized drug carriers for targeting cancer cells. CACNP is biocompatible, biodegradable and its biomaterial is readily available and is of low cost. In addition, CACNP is highly porous, has a large surface area which confer a high loading capacity. The pH-dependent release properties as well as its potential for surface functionalization with targeting agents make CACNP useful in passive and active targeting of cancer cells and cancer stem cells. In this article, we reviewed the current state of CACNP as nano-sized drug carrier for targeting cancer cells, cancer stem cells and its biocompatibility.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Veterinary Medicine Institute of Bioscience |
| DOI Number: | https://doi.org/10.1186/s12645-020-00067-3 |
| Publisher: | Springer |
| Keywords: | Calcium carbonate nanoparticle; Cockle shell; Biocompatibility; Cancer therapy |
| Depositing User: | Ms. Nuraida Ibrahim |
| Date Deposited: | 18 May 2022 03:12 |
| Last Modified: | 18 May 2022 03:12 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/s12645-020-00067-3 |
| URI: | http://psasir.upm.edu.my/id/eprint/88180 |
| Statistic Details: | View Download Statistic |
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