Citation
Abstract
The present study focused on the phytochemical profiling along with evaluation of in vitro antioxidant, α-glucosidase and α-amylase inhibitory activities of various crudes and fractions obtained from Lepisanthes fruticosa (Roxb) Leenh fruit. Ethanolic seed crude extract exhibited the strongest radical scavenging, β-carotene bleaching activity, α-glucosidase inhibition and the highest total phenolic content (TPC). Column chromatography afforded various fractions with fraction M4 being the most potent due to the strongest radical scavenging, β-carotene bleaching, α-glucosidase inhibition and greatest amount of TPC. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis of ethanolic seed crude extract and fraction M4 showed the presence of various phytochemicals with antioxidant and antidiabetic properties, which include mostly flavonoids and tannins. The results may suggest that the ethanolic crude seed extract and its fraction could be an excellent source of bioactive phytochemicals with antioxidant and antidiabetic potential.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Biotechnology and Biomolecular Sciences Faculty of Medicine and Health Science Faculty of Science |
| DOI Number: | https://doi.org/10.1016/j.foodchem.2020.127240 |
| Publisher: | Elsevier BV |
| Keywords: | Lepisanthes fruticosa; Antioxidantα-Glucosidase; α-Amylase; LC-MS/MS; Phenolics |
| Depositing User: | Ms. Zaimah Saiful Yazan |
| Date Deposited: | 17 May 2024 04:10 |
| Last Modified: | 17 May 2024 04:10 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.foodchem.2020.127240 |
| URI: | http://psasir.upm.edu.my/id/eprint/87148 |
| Statistic Details: | View Download Statistic |
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