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Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review


Citation

Tan, Wendy and Abd Ghani, Fauzah and Lim, Christopher Thiam Seong (2019) Partially reversible acute renal cortical necrosis secondary to hyperhomocysteinemia - a case report and literature review. Indian Journal of Nephrology, 29 (4). pp. 288-290. ISSN 0971-4065; ESSN: 1998-3662

Abstract

Acute renal cortical necrosis (ACN) is a potentially fatal renal condition. Our objective is to report a case of ACN in a young man who had developed premature atherosclerotic vascular disease and required intermittent hemodialysis support. His renal biopsy showed diffuse cortical necrosis. Subsequently, 2 weeks after the renal insult, he developed a cardioembolic stroke and was anticoagulated with low-molecular-weight heparin. Thrombophilia screen revealed elevated serum homocystein and he was treated with folate supplement and vitamin B12 injection. With these treatments, he had partial renal recovery and became dialysis independent. In conclusion, this is a rare case of ACN, which may have occurred as a complication of hyperhomocysteinemia.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.4103/ijn.IJN_153_18
Publisher: Medknow Publications (India)
Keywords: Acute cortical necrosis; Acute kidney injury; Hyperhomocysteinemia
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 02 Nov 2020 17:50
Last Modified: 02 Nov 2020 17:50
Altmetrics: https://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.4103/ijn.IJN_153_18
URI: http://psasir.upm.edu.my/id/eprint/81616
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