Citation
Abstract
Postbiotics (bioactives) are nonviable metabolites produced by probiotics that exert biological effects on the hosts. The myriad beneficial effects of postbiotics produced by six novel bacteriocinogenic Lactobacillus plantarum strains have been proven extensively since 2004, with the broad bacteriocin inhibitory activity against various pathogens, as they harbor two classes of bacteriocin structural genes (plnEF and pln W). The supplementation of the postbiotics to various animal models has significantly improved serum cholesterol, immune response, overall health, and growth, while suppressing the population of pathogenic bacteria in the digestive tract. Additionally, the postbiotics of these lactobacilli strains demonstrated novel antiproliferation and anticancer activity against various human cancer cell lines by inducing cytotoxicity via apoptotic pathway.
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Additional Metadata
Item Type: | Book Section |
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Divisions: | Faculty of Agriculture Faculty of Biotechnology and Biomolecular Sciences Institute of Bioscience Institute of Tropical Agriculture and Food Security |
DOI Number: | https://doi.org/10.1016/B978-0-12-815249-2.00021-X |
Publisher: | Academic Press |
Keywords: | Antiproliferation; Antibiotic growth promoter; Cytotoxicity; Food additives; Lactobacillus plantarum; Postbiotic |
Depositing User: | Azhar Abdul Rahman |
Date Deposited: | 03 Aug 2021 10:01 |
Last Modified: | 03 Aug 2021 10:01 |
Altmetrics: | http://altmetrics.com-details.php?domain=psair.upm.edu.my&doi=10.1016/B978-0-12-815249-2.00021-X |
URI: | http://psasir.upm.edu.my/id/eprint/78995 |
Statistic Details: | View Download Statistic |
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