Pattern of haematology and serum biochemistry parameters in cats suspected of feline infectious peritonitis presented to University Veterinary Hospital, Universiti Putra Malaysia from the year 2014 to 2016

Feline Infectious Peritonitis (FIP) is a lethal immunopathological disease caused by mutated feline enteric coronavirus found in both wild and domesticated cats. There are limited local studies on the pattern of haematological and serum biochemical parameters in FIP cats. Thus, this study was conducted to determine the pattern of haematological and serum biochemical parameters in suspected FIP cats presented to UVH, UPM and also to compare these parameters between dry form and wet form FIP. Medical records of cats suspected of FIP with compatible history and clinical signs admitted to UVH from year 2014 to 2016 were reviewed and the sole inclusion criterion was cats tested for FCoV antibody using dot-ELISA, Biogal‘s Immunocomb® Feline Coronavirus Antibody Test Kit with medium to high positive FCoV antibody titre (S3-S6). Data on signalment (age, sex and breed), haematology and serum biochemistry results were obtained. Among the 132 suspected FIP cats, 81.1% had hyperproteinaemia, 88.6% had hyperglobulinaemia, 97.7% had A:G ratio≤ 0.8 and46.2% had hypoalbuminaemia, 47.8% had neutrophilia with left shift, 44.7% had lymphopaenia, 41.7% had monocytosis, 55.3% had eosinopaenia, and 31.8% had nonregenerative anaemia. Parameters such as lymphocyte count (P=0.002), eosinophil count (P=0.009), total protein (P=0.000), albumin (P=0.000), globulin (P=0.041), ALT (P=0.016), ALP (P=0.025) and creatinine (P=0.047) were found to be significantly different between dry form and wet form FIP.

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