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Misleading free thyroxine (FT4): a case report


Citation

Hashim, Nurul Hidayah and Samsudin, Intan Nureslyna and Masiman, Ana Daliela and Chellappah Thambiah, Subashini (2020) Misleading free thyroxine (FT4): a case report. Malaysian Journal of Medicine and Health Sciences, 16 (2). pp. 320-322. ISSN 1675-8544; ESSN: 2636-9346

Abstract

Interpretation of thyroid function test (TFT) is often straightforward but in certain scenarios, discordance between the clinical impression and the laboratory results exists. A 50-year-old woman with a ten years history of hypothyroidism on levothyroxine presented with a recent notable change in TFT [elevated free thyroxine (FT4) and thyroid-stimulating hormone (TSH)], in an otherwise clinically euthyroid and previously stable TFT, leading to levothyroxine being withheld. This case report highlights the possibility of assay interference as a cause of discordant TFT. It also draws the importance of close collaboration between clinicians and the laboratory to avoid unnecessary investigations and inappropriate management of such a case.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Keywords: Hypothyroidism; Immunoassay; Thyroxine; Thyroid function test (TFT)
Depositing User: Nabilah Mustapa
Date Deposited: 04 May 2020 17:49
Last Modified: 04 May 2020 17:49
URI: http://psasir.upm.edu.my/id/eprint/77948
Statistic Details: View Download Statistic

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