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Small cell neuroendocrine carcinoma: a rare second primary malignancy after treatment of nasopharyngeal carcinoma


Citation

Madhusudhan, Krishnamoorthy and Hassan, Nor Eyzawiah and Md Shukri, Norasnieda and Hitam, Shahrul and Bakrin, Ikmal Hisyam (2018) Small cell neuroendocrine carcinoma: a rare second primary malignancy after treatment of nasopharyngeal carcinoma. Romanian Journal of Rhinology, 8 (31). 187 - 192. ISSN ESSN: 2393-3356

Abstract

Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.2478/rjr-2018-0021
Publisher: Sciendo
Keywords: Neuroendocrine carcinoma; Nasopharyngeal carcinoma; Second primary malignancy; Small cell carcinoma
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 17 May 2020 17:17
Last Modified: 17 May 2020 17:17
Altmetrics: https://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2478/rjr-2018-0021
URI: http://psasir.upm.edu.my/id/eprint/73906
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