Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis

Citation

Fuah, Kar Wah and Lim, Christopher Thiam Seong and Pang, Daniel C. L. and Jin, Shyan Wong (2018) Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis. Saudi Journal of Kidney Diseases and Transplantation, 29 (1). 207 - 209. ISSN 1319-2442

Abstract

Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property. In patients with renal impairment, even administering the usual recommended dose of TXA can induce seizure episodes. We present here a patient on hemodialysis who developed seizures after receiving two doses of TXA over 5 h period.

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Additional Metadata

Item Type:	Article
Divisions:	Faculty of Medicine and Health Science
DOI Number:	https://doi.org/10.4103/1319-2442.225177
Publisher:	Wolters Kluwer Medknow Publications
Keywords:	Tranexamic acid; Kidney disease
Depositing User:	Ms. Nida Hidayati Ghazali
Date Deposited:	20 May 2020 09:08
Last Modified:	20 May 2020 09:08
Altmetrics:	https://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.4103/1319-2442.225177
URI:	http://psasir.upm.edu.my/id/eprint/73846
Statistic Details:	View Download Statistic

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