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Role of herbal medicines in vitiligo treatment - current status and future perspectives


Citation

Narayanaswamy, Radhakrishnan and Ismail, Intan Safinar (2018) Role of herbal medicines in vitiligo treatment - current status and future perspectives. Asian Journal of Pharmaceutical and Clinical Research, 11 (9). 19 - 23. ISSN 0974-2441; ESSN 2455-3891

Abstract

Vitiligo is a depigmentation disorder with complex causes. Nonetheless, recent progress has been made to unravel the pathophysiology of vitiligo. In this review, we provide an overview of the currently known herbal medicine for vitiligo treatment and also highlighted the herbs that have been used in clinical trials. In view of traditional uses, herbs such as Ammi visnaga L., Angelica sinensis, Eclipta alba L, Ginkgo biloba, Picrorhiza kurroa Royle Ex Benth, and Psoralea corylifolia L, have been highlighted. Enormous efforts in vitiligo drug discovery are currently needed. Interleukin-17 inhibition, tumor necrosis factor-alpha inhibition, heat shock protein-70i (HSP70i) inhibition, keratinocyte turnover modulators, and regulatory T cells (Tregs) modulators have been discussed as promising new targets for vitiligo drug development. Thus, we strongly believe that this review may be useful for rationalize new herbal drug for vitiligo treatment.


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Additional Metadata

Item Type: Article
Divisions: Institute of Bioscience
DOI Number: https://doi.org/10.22159/ajpcr.2018.v11i9.26830
Publisher: Innovare Academic Sciences
Keywords: Vitiligo; Melanocyte; Ammi visnaga; Psoralea corylifolia; Regulatory T cells (Tregs) modulators
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 06 May 2020 18:36
Last Modified: 06 May 2020 18:36
Altmetrics: https://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.22159/ajpcr.2018.v11i9.26830
URI: http://psasir.upm.edu.my/id/eprint/73818
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