Citation
Mohd Bakhori, Siti Aisyah and Mohd Zaki, Nor Nadiha and Mat Hashim, Dzulkifly
(2014)
Rheological analysis of gelatine and new developed substitute (plant base material) in halal capsule development.
In: Malaysia International Halal Research & Education Conference 2014 (MIHREC 2014), 2-4 Dec. 2014, Marriott Putrajaya Hotel, Malaysia. (p. 308).
Abstract
The most abundant sources of gelatin production are pig skin, contributing about 50% of total gelatin production in 2007. Gelatin is widely used as major ingredient in capsule production because of its unique properties which is best in delivering active pharmaceutical ingredients (API). Gelatin capsule is easily melted in water at a temperature above 30 °C and will release encapsulated drugs into the human digestive tract due to temperature, gastric pH and the action of digestive enzymes. However, religious and ethics restrict the use of animal based materials in capsules and required the development of gelatin alternatives. Rheological methods were used as tools to compare and understand the rheological behaviour between gelatin and the newly developed substitute (plant base material). From this research, the gelatin’s melting and gelling temperatures were set as a bench mark for the newly developed substitute besides studying the viscosity and gel rigidity properties.The benefits of having the rheological data as a guideline to optimize the appropriate parameters and rheological behaviours of the newly developed substitute.
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