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A review on the effects of prebiotics on cell toxicity and integrity


Citation

Mundi, Morven and Mikal, Kathleen Michelle and Ahmed, Osumanu Haruna and Sarbini, Shahrul Razid (2017) A review on the effects of prebiotics on cell toxicity and integrity. International Journal of Food Properties, 20 (supp. 1). pp. 1-8. ISSN 1094-2912; ESSN: 1532-2386

Abstract

Prebiotics are known as the ‘food’ for beneficial gut microbiota that are capable of promoting host health. Their effects depend on the product of gut fermentation or metabolites. This paper discusses the role of prebiotics on cytotoxicity, genotoxicity, and cell integrity. Metabolites produced from the fermentation of prebiotics can be used to understand gut diseases such as colorectal cancer. Fecal water from in vivo or in vitro studies can be used to understand the relationship between prebiotics and gut diseases because of its close contact with colon epithelium. Besides, fecal water has compounds that are capable of modifying colonocytes.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture and Food Sciences
DOI Number: https://doi.org/10.1080/10942912.2017.1326937
Publisher: Taylor & Francis
Keywords: Beneficial microbes; Cell integrity; Cytotoxicity; Fecal water; Genotoxicity; Prebiotics; Probiotics
Depositing User: Ms. Nida Hidayati Ghazali
Date Deposited: 29 Apr 2019 05:28
Last Modified: 29 Apr 2019 05:28
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1080/10942912.2017.1326937
URI: http://psasir.upm.edu.my/id/eprint/60725
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