Citation
Abstract
Breast cancer is the most common malignancy worldwide, especially among women, with substantial after-treatment effects. The survival rates of breast cancer have decreased over the years even with the existence of various therapeutic strategies, specifically, chemotherapy. Clinical drugs administered for breast cancer appear to be non-targeting to specific cancer sites leading to severe side effects and potentially harming healthy cells instead of just killing cancer cells. This leads to the need for designing a targeted drug delivery system. Nanomaterials, both organic and inorganic, are potential drug nanocarriers with the ability of targeting, imaging and tracking. Various types of nanomaterials have been actively researched together with their drug conjugate. In this review, we focus on selected nanomaterials, namely solid-lipid, liposomal, polymeric, magnetic nanoparticles, quantum dots, and carbon nanotubes and their drug conjugates, for breast cancer studies. Their advantages, disadvantages and previously conducted studies were highlighted.
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Official URL or Download Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC53762...
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Additional Metadata
Item Type: | Article |
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Divisions: | Faculty of Medicine and Health Science Faculty of Science Institute of Bioscience |
DOI Number: | https://doi.org/10.2147/IJN.S127329 |
Publisher: | Hindawi Publishing Corporation |
Keywords: | Advantages; Breast cancer; Disadvantages; Nanomedicine; Therapeutic strategies |
Depositing User: | Ms. Nida Hidayati Ghazali |
Date Deposited: | 02 Apr 2019 02:19 |
Last Modified: | 02 Apr 2019 02:19 |
Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2147/IJN.S127329 |
URI: | http://psasir.upm.edu.my/id/eprint/60716 |
Statistic Details: | View Download Statistic |
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