Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica

Citation

Lawal, Umar and Shaari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2016) Antioxidant and α-glucosidase inhibitory activities of isolated compounds from ipomoea aquatica. Records of Natural Products, 10 (6). pp. 701-707. ISSN 1307-6167

Abstract

Ipomoea aquatica Forsk is a green leafy vegetable that is a rich source of amino acids and vitamins. Antioxidant and α-glucosidase inhibitory activities of the hexane (IAHE) and methanol (IAME) fractions of the vegetable portion of I. aquatica were investigated. The IAME fraction exhibited a strong scavenging effect of the 2,2-diphenyl-2-picryl hydrazyl (DPPH) free radicals, and this fraction contained the highest phenolic contents. Phytochemical investigation of the IAME fraction yielded three known compounds, namely 3,5-di-O-caffeoylquinic acid (1), 4,5-di-O-caffeoylquinic acid (2) and quercetin 3-O-β-D-glucoside (3). The structures were unambiguously elucidated based on 1D and 2D-NMR analyses (1H, 13C, COSY, HSQC, HMBC) and mass spectrometry data. Compound 3 was isolated for the first time from this plant.

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Additional Metadata

Item Type:	Article
Divisions:	Faculty of Food Science and Technology Institute of Bioscience
Publisher:	ACG Publications
Keywords:	Antioxidant activity; Total phenolic content; α-glucosidase inhibition; Spectral analysis
Depositing User:	Mohd Hafiz Che Mahasan
Date Deposited:	13 Aug 2018 07:44
Last Modified:	13 Aug 2018 07:44
URI:	http://psasir.upm.edu.my/id/eprint/55090
Statistic Details:	View Download Statistic

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