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Simulation of left-truncated and case-k interval censored survival data with time-varying covariates


Citation

Manoharan, Thirunanthini and Arasan, Jayanthi and Midi, Habshah and Adam, Mohd Bakri (2016) Simulation of left-truncated and case-k interval censored survival data with time-varying covariates. Malaysian Journal of Mathematical Sciences, 10 (spec. Aug.). pp. 159-173. ISSN 1823-8343; ESSN: 2289-750X

Abstract

This research focuses on simulation of left-truncated and case-k interval censored survival data from the log-normal model with a time-varying covariate. Left-truncated data usually arises in prevalence cohort study where randomly selected individuals from medical records may have contracted certain disease for some duration of time but are free from event of interest at time of entry into a survival study. In this research, we proposed a simulation methodology by fixing the percentage of truncation at 20% and 60% with the width of 4 months of inspection interval. The procedure was computationally demanding due to the presence of left-truncation and time-varying covariates. The suitability of the proposed method was assessed based on the bias, standard error and root mean square of the parameter estimates for the log-normal survival model.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
Institute for Mathematical Research
Publisher: Institute for Mathematical Research, Universiti Putra Malaysia
Notes: Special issue: The 7th International Conference on Research and Education in Mathematics (ICREM7)
Keywords: Simulation; Left-truncation; Case-k interval censored; Time-varying covariates; Log-normal distribution
Depositing User: Nabilah Mustapa
Date Deposited: 05 Jun 2017 09:35
Last Modified: 05 Jun 2017 09:35
URI: http://psasir.upm.edu.my/id/eprint/52365
Statistic Details: View Download Statistic

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