Xanthone from Garcinia eugenifolia (Clusiaceae)

Citation

Jong, Vivien Yi Mian and Ee, Gwendoline Cheng Lian and Khong, Heng Yen (2010) Xanthone from Garcinia eugenifolia (Clusiaceae). In: 2010 International Conference on Science and Social Research (CSSR 2010), 5-7 Dec. 2010, Seri Pacific Hotel, Kuala Lumpur, Malaysia. (pp. 786-788).

Abstract

Studies on the twigs of Garcinia eugenifolia have led to the isolation of one xanthone 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)pyrano[3,2-b]xanthen-6(2H)-one (1) and one triterpenoid, sitosterol (2). Meanwhile, studies on the leaves of Garcinia eugenifolia provided another triterpenoid, friedelin (3). The structures of these compounds were determined by spectroscopic methods such as 1H NMR, 13C NMR, mass spectrometry (MS) and by comparison with previous studies. The hexane and ethyl acetate extracts of Garcinia eugenifolia indicated strong cytotoxicity towards the HL-60 cell line with IC50 values of 1.9 μg/ml and 2.5 μg/ml respectively. However, the methanol extract gave moderate inhibitory activities (IC50<10 μg/ml) towards HL-60 cell line.

Download File

Text (Abstract)
Xanthone from Garcinia eugenifolia (Clusiaceae).pdf
Download (48kB)

Additional Metadata

Item Type:	Conference or Workshop Item (Paper)
Divisions:	Faculty of Science
DOI Number:	https://doi.org/10.1109/CSSR.2010.5773892
Publisher:	IEEE
Keywords:	Garcinia eugenifolia; Xanthone; Cytotoxicity
Depositing User:	Nabilah Mustapa
Date Deposited:	07 Aug 2020 02:27
Last Modified:	07 Aug 2020 02:27
Altmetrics:	http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1109/CSSR.2010.5773892
URI:	http://psasir.upm.edu.my/id/eprint/45685
Statistic Details:	View Download Statistic

Actions (login required)

View Item