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Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats


Citation

Mohd Esa, Norhaizan and Tan, Bee Ling and Ithnin, Hairuszah and Hamzah, Hazilawati and Karim, Roselina (2015) Brewers' rice, a by-product from rice processing provides natural hepatorenal protection in azoxymethane-induced oxidative stress in rats. Oxidative Medicine and Cellular Longevity, 2015. art. no. 539798. pp. 1-10. ISSN 1942-0900; ESSN: 1942-0994

Abstract

Brewers’ rice, which is known locally as temukut, is a mixture of broken rice, rice bran, and rice germ. Our present study was designed to identify the effect of brewers’ rice on the attenuation of liver and kidney damage induced by azoxymethane (AOM). Alanine transaminase (ALT), alkaline phosphatase (ALP), aspartate transaminase (AST), creatinine, and urea were evaluated to understand potential hepatoprotective effects and the ability of brewers’ rice to attenuate kidney pathology induced by AOM treatment. Liver and kidney tissues were evaluated by hematoxylin and eosin (H&E) staining. Overall analyses revealed that brewers’ rice improved the levels of serum markers in a manner associated with better histopathological outcomes, which indicated that brewers’ rice could enhance recovery from hepatocyte and kidney damage. Taken together, these results suggest that brewers’ rice could be used in future applications to combat liver and kidney disease.


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Official URL or Download Paper: https://www.hindawi.com/journals/omcl/2015/539798/

Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
Faculty of Medicine and Health Science
Faculty of Veterinary Medicine
Institute of Bioscience
DOI Number: https://doi.org/10.1155/2015/539798
Publisher: Hindawi
Keywords: Brewers' rice; Rice processing; Hepatorenal protection; Rats
Depositing User: Ms. Ainur Aqidah Hamzah
Date Deposited: 01 Dec 2021 07:01
Last Modified: 01 Dec 2021 07:01
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2015/539798
URI: http://psasir.upm.edu.my/id/eprint/43973
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