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A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data


Citation

Shi, Jing Lu and Muzaffar Shah, Farah Fathiah and Mohamad, Mohd Saberi and Moorthy, Kohbalan and Deris, Safaai and Zakaria, Zalmiyah and Napis, Suhaimi (2015) A review on bioinformatics enrichment analysis tools towards functional analysis of high throughput gene set data. Current Proteomics, 12 (1). pp. 14-27. ISSN 1570-1646; ESSN: 1875-6247

Abstract

The emergence of high throughput data in genomic, proteomic and bioinformatics has increased the necessity to develop large amount of functional analysis tools to facilitate the inference of biologically meaningful data. A promising high throughput strategy, which is the gene-annotation enrichment analysis, can increase the elucidation ability of related biological processes. This paper reviews 35 bioinformatics enrichment tools and 5 gene set databases that are currently available in the field, which include the description of these tools and databases. This information can help tool developers and users to gain a broad view and better understanding on the bioinformatics enrichment tools and databases, enabling a better decision making in choosing tools in particular research interest.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
DOI Number: https://doi.org/10.2174/157016461201150506200927
Publisher: Bentham Science Publishers
Keywords: Bioinformatics; Database; Enrichment tools; Functional analysis; Gene set data; Software
Depositing User: Mohd Hafiz Che Mahasan
Date Deposited: 21 Jul 2016 04:52
Last Modified: 21 Jul 2016 04:52
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2174/157016461201150506200927
URI: http://psasir.upm.edu.my/id/eprint/43575
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