Citation
Abdul Karim, Mohamad Nordin
(1989)
The effects of propranolol and chlorisondamine on amphetamine hyperthermic action on brown adipose tissue in lean and obese zucker rats.
Jurnal Sains Nuklear Malaysia, 7 (2).
pp. 91-96.
ISSN 2232-0946
Abstract
Thermogenic capacity of brown adipose tissue was measured by [3H] GDP binding on the mitochondrial preparation of the tissue. Obese Zucker Rats are found to be more sensitive to amphetamine compared to the lean genotype. Amphetamine stimulation involves β - receptors and is centrally controlled. Increase in thermogenesis by amphetamine does not involve stimulation of the mitochondrial enzymic activity.
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