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Dissolution profiling and its comparison of natural fruit powder effervescent tablets


Citation

Saifullah, M. and Yusof, Yus Aniza and Chin, Nyuk Ling and Aziz, Mohammad Gulzarul and P. Mohammed, Mohd Afandi and Abdul Aziz, Norashikin (2016) Dissolution profiling and its comparison of natural fruit powder effervescent tablets. Journal of Food Engineering, 178. pp. 60-70. ISSN 0260-8774; ESSN: 1873-5770

Abstract

The aims of the study were to observe the dissolution profile of four types of selected fruit powder fast dissolve tablet and apply different dissolution profile comparison methods, in order to select most applicable method. Spray dried powder of pitaya, pineapple, guava and mango were used as raw material. Each type of fruit powder tablet has identical dissolution profile. Dissolution profiles and dissolution rate of fruit powder tablets were different at different dissolution environment. In model-independent and statistical method pairwise comparison was performed and in model dependent method profile comparison was carried out based on best fitting of mathematical model equation. Dissolution Profile comparison methods represented that model independent method use wide range of value for profile comparison and it was direct and easy; model dependent method was indirect and complex and for critically compare the dissolution profile statistical method was the most suitable method.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Engineering
DOI Number: https://doi.org/10.1016/j.jfoodeng.2016.01.007
Publisher: Elsevier
Keywords: Fruit powder tablet; Dissolution profiling; Profile comparison; Model dependent method; Model independent method; Statistical method
Depositing User: Nabilah Mustapa
Date Deposited: 18 May 2016 04:11
Last Modified: 18 May 2016 04:11
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.jfoodeng.2016.01.007
URI: http://psasir.upm.edu.my/id/eprint/43205
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