Citation
Tan, Seok Shin and Allaudin, Zeenathul Nazariah and Mohd Lila, Mohd Azmi
(2011)
Adenoviral based gene therapy for cancer in human and animals: a review.
Pertanika Journal of Science & Technology, 19 (1).
pp. 129-140.
ISSN 0128-7680; ESSN: 2231-8526
Abstract
Adenovirus vector is the most common used vector in clinical gene therapy. The development of adenovirus from the first generation until the helper-dependent adenovirus vector has greatly reduced toxicity and immunogenicity. The helper-dependent adenovirus can also prolong transgene expression. Tissue- or disease-specific approach has been used to improve the specificity of adenoviral vector for cancer gene therapy. This review summarizes some adenoviral gene therapy and targeting approaches available for human cancer as well as animal cancer.
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Official URL or Download Paper: http://www.pertanika.upm.edu.my/Pertanika%20PAPERS...
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Veterinary Medicine |
| Publisher: | Universiti Putra Malaysia Press |
| Keywords: | Adenovirus vector; Clinical; Gene therapy; Human cancer; Animal cancer |
| Depositing User: | Noor Syafini Zamani |
| Date Deposited: | 23 Nov 2015 01:44 |
| Last Modified: | 05 Jan 2016 08:58 |
| URI: | http://psasir.upm.edu.my/id/eprint/40590 |
| Statistic Details: | View Download Statistic |
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