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Excretion of purine derivatives in cows: endogenous contribution and recovery of exogenous purine bases


Citation

Boero, P. Orellana and Balcells, Joaquim and Martin-Orue, Susana Maria and Liang, Juan Boo and Guada, Jose Antonio (2001) Excretion of purine derivatives in cows: endogenous contribution and recovery of exogenous purine bases. Livestock Production Science, 68 (2-3). pp. 243-250. ISSN 0301-6226

Abstract

Two dry cows fitted with simple cannula in the rumen and duodenum, and fed with a mixed diet (straw:barley, 50:50), were used to determine endogenous losses and response of urinary purine derivatives (PDs) to duodenally infused yeast-RNA. Duodenal flow of purine bases (PBs) was determined by a dual marker system, and 15N was infused continuously into the rumen to label microbial PBs. The isotope dilution of urinary PDs in relation to duodenal PBs confirmed the presence of an endogenous fraction (236 μmol/kg LW0.75) bigger than in sheep and lower than values estimated in cows with impaired rumen fermentation. Excretion of PDs increased linearly in response to incremental supply of PBs with an equimolar recovery of 0.84 mol/mol. However, net recovery of duodenal PBs was 0.67 for the basal diet and 0.65, 0.90, 0.79 and 0.82 for the four levels of PB infusion. It is suggested that differences in digestibility between yeast-RNA and duodenal PBs might explain differences in recovery estimations.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
DOI Number: https://doi.org/10.1016/S0301-6226(00)00231-1
Publisher: Elsevier
Keywords: Cattle – feeding and nutrition; Nucleic acid; Purine derivatives; Allantoin
Depositing User: Nabilah Mustapa
Date Deposited: 17 Sep 2015 08:48
Last Modified: 17 Sep 2015 08:48
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/S0301-6226(00)00231-1
URI: http://psasir.upm.edu.my/id/eprint/40377
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