UPM Institutional Repository

In vitro inhibition of acetylcholinesterase by acephate and methamidophos


Citation

Mohamad, Rosli (1990) In vitro inhibition of acetylcholinesterase by acephate and methamidophos. Journal of Plant Protection in the Tropics, 7 (1). pp. 55-61. ISSN 0127-6883

Abstract

Inhibition of the acetylcholinesterase (AChE) of two insects, laboratory rat and human by acephate and methamidophos insecticides was evaluated in vitro. Acephate in itself is capable of inhibiting AChE to some extent, immediately as well as for a prolonged period. The inhibition by methamidophos progressed faster during the first 20 to 30 min of exposure, but not immediately. The pattern of inhibition of the AChE by both insecticides followed that of paraoxon, and are non-reversible. Incubation of AChE with acephate and methamidophos together did not produce inhibition of synergistic effect but could only be considered as additive


Download File

[img] PDF
aar 177 In Vitro Inhibition Of Acetylcholinesterase By Acephate And.pdf
Restricted to Repository staff only

Download (375kB)

Additional Metadata

Item Type: Article
Divisions: Faculty of Agriculture
Universiti Pertanian Malaysia
Publisher: Malaysian Plant Protection Society
Keywords: In vitro inhibition; Acetylcholinesterase; Acephate; Methamidophos
Depositing User: Azhar Abdul Rahman
Date Deposited: 11 Jan 2016 07:05
Last Modified: 11 Jan 2016 07:05
URI: http://psasir.upm.edu.my/id/eprint/39120
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item