Citation
Mohamad, Rosli
(1990)
In vitro inhibition of acetylcholinesterase by acephate and
methamidophos.
Journal of Plant Protection in the Tropics, 7 (1).
pp. 55-61.
ISSN 0127-6883
Abstract
Inhibition of the acetylcholinesterase (AChE) of two insects, laboratory rat and human by acephate and methamidophos insecticides was evaluated in vitro. Acephate in itself is capable of inhibiting AChE to some extent, immediately as well as for a prolonged period. The inhibition by methamidophos progressed faster during the first 20 to 30 min of exposure, but not immediately. The pattern of inhibition of the AChE by both insecticides followed that of paraoxon, and are non-reversible. Incubation of AChE with acephate and methamidophos together did not produce inhibition of synergistic effect but could only be considered as additive
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Agriculture Universiti Pertanian Malaysia |
| Publisher: | Malaysian Plant Protection Society |
| Keywords: | In vitro inhibition; Acetylcholinesterase; Acephate; Methamidophos |
| Depositing User: | Azhar Abdul Rahman |
| Date Deposited: | 11 Jan 2016 07:05 |
| Last Modified: | 11 Jan 2016 07:05 |
| URI: | http://psasir.upm.edu.my/id/eprint/39120 |
| Statistic Details: | View Download Statistic |
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