Citation
Abstract
Plant natural compounds have great potential as alternative medicines for preventing and treating diseases. Melicope lunu-ankenda is one Melicope species (family Rutaceae), which is widely used in traditional medicine, consumed as a salad and a food seasoning. Consumption of different parts of this plant has been reported to exert different biological activities such as antioxidant and anti-inflammatory qualities, resulting in a protective effect against several health disorders including neurodegenerative diseases. Various secondary metabolites such as phenolic acid derivatives, flavonoids, coumarins and alkaloids, isolated from the M. lunu-ankenda plant, were demonstrated to have neuroprotective activities and also exert many other beneficial biological effects. A number of studies have revealed different neuroprotective mechanisms for these secondary metabolites. This review summarizes the most significant and recent studies for neuroprotective activity of M. lunu-ankenda major secondary metabolites in neurodegenerative diseases.
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Official URL or Download Paper: https://www.mdpi.com/1420-3049/24/17/3109
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Additional Metadata
Item Type: | Article |
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Divisions: | Faculty of Food Science and Technology Faculty of Science Institute of Bioscience Institute of Tropical Agriculture and Food Security |
DOI Number: | https://doi.org/10.3390/molecules24173109 |
Publisher: | MDPI |
Keywords: | Polyphenols; Coumarins; Alkaloids; Melicope lunu-ankenda; Neuroprotection; Neurodegenerative diseases |
Depositing User: | Nabilah Mustapa |
Date Deposited: | 04 May 2020 16:11 |
Last Modified: | 04 May 2020 16:11 |
Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules24173109 |
URI: | http://psasir.upm.edu.my/id/eprint/38283 |
Statistic Details: | View Download Statistic |
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