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Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats


Citation

Movahedi, Ariyo and Basir, Rusliza and Rahmat, Asmah and Charaffedine, Mohammad and Othman, Fauziah (2014) Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats. Evidence-Based Complementary and Alternative Medicine, 2014. art. no. 726724. pp. 1-9. ISSN 1741-427X; ESSN: 1741-4288

Abstract

The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
DOI Number: https://doi.org/10.1155/2014/726724
Publisher: Hindawi Publishing Corporation
Keywords: Anticancer activity; Teucrium polium; Hepatocellular carcinogenic rats
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 31 Dec 2015 03:00
Last Modified: 31 Dec 2015 03:00
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2014/726724
URI: http://psasir.upm.edu.my/id/eprint/35222
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