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Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review


Citation

Shamsuddin, Aida Soraya and Syed ismail, Sharifah Norkhadijah and Mohd. Sham, Shaharuddin and Zainal Abidin, Emilia (2014) Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review. International Journal of Sciences: Basic and Applied Research, 15 (2). pp. 176-191. ISSN 2307-4531

Abstract

Nitrate is harmful to humans as it can form endogenous nitrosamines which can cause cancer. The major contribution of nitrate contamination in well water is largely from agricultural activities (e.g.; fertilizers and pesticide), wastewater treatment plant discharge, animal yard and manure storage lagoons. Biomarkers such as urine and saliva can be used to determine the occurrence and formation of nitrosamines in the human body. This paper provides an overview of nitrate occurrence in groundwater and the mechanism of nitrosamines formation and its excretion from human body via urine and saliva. The suitability of urine and saliva as biomarkers of endogenous nitrosamines formation were also discussed in this review.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Publisher: Global Society of Scientific Research and Researchers
Keywords: Groundwater; Nitrate; Nitrosamines; Urine; Saliva
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 17 Dec 2015 08:20
Last Modified: 27 Jan 2016 02:18
URI: http://psasir.upm.edu.my/id/eprint/34652
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