Citation
Abstract
Hydroxamic acids and their derivatives have low toxicities and show wide range of biological activities. Copper complexes of phenyl fatty hydroxamic acids (Cu-PFHs) were prepared in a biphasic organic / aqueous medium from phenyl fatty hydroxamic acids (PFHAs) and copper nitrate. The products were separated by decantation of organic phase from aqueous phase followed by evaporation of the solvent. Elemental analysis, UV-Vis spectra and FTIR spectra showed that Cu-PFHs were formed in the solution from the complexation of PFHAs and copper ion. The antibacterial activity of PFHAs and Cu-PFHs from canola and palm kernel oils were investigated against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) using well diffusion method. The results showed that Cu-PFHs have higher antibacterial activity compared to PFHAs. Antibacterial activity of Cu-PHAs from canola oil against E.coli was significantly higher than hloramphenicol and cefotaxime.
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Additional Metadata
Item Type: | Article |
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Divisions: | Institute of Advanced Technology Faculty of Engineering Faculty of Food Science and Technology |
Publisher: | National Institute R and D of Materials Physics |
Keywords: | Antibacterial activity; Copper phenyl fatty hydroxamate; Phenyl fatty hydroxamic acids; Canola oil; Palm kernel oil; Well diffusion methods. |
Depositing User: | Azizan Arshad |
Date Deposited: | 19 Aug 2014 04:50 |
Last Modified: | 05 Oct 2015 07:49 |
URI: | http://psasir.upm.edu.my/id/eprint/30810 |
Statistic Details: | View Download Statistic |
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