Citation
Mohd Nor, Siti Mariam and Mohd Fauzi, Nawwar Fathiah and Ismail, Intan Safinar
(2013)
Synthesis of nitrogen-substituted pyran-2-ones via radical cyclisation approach.
International Journal of Education and Research, 1 (6).
ISSN 2201-6333; ESSN: 2201-6740
Abstract
Four new4-N-substituted pyran-2-ones (δ-lactones) were successfully synthesised from their corresponding cyanoalcohols via two reaction steps; (i) acylation and (ii) radical cyclisation. Four cyanobromoesters that were produced from acylation were treated with tris(trimethylsilyl)silane (TTMSH) and azobisisobutyronitrile (AIBN) in toluene to obtain 5-hydro-4-imino-3,6- dimethylpyran-2-one (4a), 4-amino-5-hydro-3,6,6-trimethylpyran-2-one (4b),3,5-dihydro-4-imino- 6-methylpyran-2-one (4c), and 3,5-Dihydro-4-imino-6,6-dimethylpyran-2-one (4d).
Download File
Official URL or Download Paper: http://www.ijern.com/June-2013.php
|
Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Science Institute of Bioscience |
| Publisher: | Contemporary Research Center, Australia |
| Keywords: | Pyran-2-one; 3-ene-lactones; Radical cyclisation; TTMSH; AIBN; 6-exo-dig. |
| Depositing User: | Umikalthom Abdullah |
| Date Deposited: | 23 Oct 2014 06:22 |
| Last Modified: | 09 Oct 2015 00:40 |
| URI: | http://psasir.upm.edu.my/id/eprint/30288 |
| Statistic Details: | View Download Statistic |
Actions (login required)
 |
View Item |