Citation
Abstract
The structural and dynamics properties of the bilayer comprising 128 molecules of dipalmitoylphosphatidylcholine (DPPC), dilauroylphosphatidylcholine (DLPC), dimyristoylphosphatidylcholine (DMPC), and distearoylphosphatidylcholine (DSPC) in water were investigated using a coarse-grained molecular dynamics (CG-MD) simulation technique. The model mixture system was simulated at 298 K under semi-isotropic pressure conditions. The aggregation was initiated from the random configurations followed by the formation of a bilayer over a period of 500 ns. The calculated values of the area per lipid, thickness, and lateral diffusion for the mixed model were different from when a single lipid was used. Our results confirmed that the chain length of the lipid molecules strongly affects the phospholipid bilayer's physical properties.
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Official URL or Download Paper: http://www.hindawi.com/journals/jchem/2013/931051/
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Biotechnology and Biomolecular Sciences Faculty of Science Institute of Bioscience |
| DOI Number: | https://doi.org/10.1155/2013/931051 |
| Publisher: | Hindawi Publishing Corporation |
| Keywords: | Dipalmitoylphosphatidylcholine; Dilauroylphosphatidylcholine; Dimyristoylphosphatidylcholine, Distearoylphosphatidylcholine; Self-assembly; Coarse-grained molecular dynamics. |
| Depositing User: | Umikalthom Abdullah |
| Date Deposited: | 10 Sep 2014 02:45 |
| Last Modified: | 18 Sep 2015 08:00 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1155/2013/931051 |
| URI: | http://psasir.upm.edu.my/id/eprint/30177 |
| Statistic Details: | View Download Statistic |
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