Citation
Abstract
Background: Zinc layered hydroxide (ZLH) intercalated with cinnamate, an anionic form of cinnamic acid (CA), an efficient UVA and UVB absorber, have been synthesized by direct method using zinc oxide (ZnO) and cinnamic acid as the precursor. Results: The resulting obtained intercalation compound, ZCA, showed a basal spacing of 23.9 Å as a result of cinnamate intercalated in a bilayer arrangement between the interlayer spaces of ZLH with estimated percentage loading of cinnamate of about 40.4 % w/w. The UV–vis absorption spectrum of the intercalation compound showed excellent UVA and UVB absorption ability. Retention of cinnamate in ZLH interlayers was tested against media usually came across with sunscreen usage to show low release over an extended period of time. MTT assay of the intercalation compound on human dermal fibroblast (HDF) cells showed cytotoxicity of ZCA to be concentration dependent and is overall less toxic than its precursor, ZnO. Conclusions: (Cinnamate-zinc layered hydroxide) intercalation compound is suitable to be used as a safe and effective sunscreen with long UV protection effect.
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Official URL or Download Paper: http://ccj.springeropen.com/articles/10.1186/1752-...
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science Faculty of Science Institute of Bioscience Institute of Advanced Technology |
| DOI Number: | https://doi.org/10.1186/1752-153X-7-26 |
| Publisher: | Chemistry Central |
| Keywords: | Cytotoxicity; Optical properties; Sunscreen; Zinc layered hydroxide; Zinc oxide |
| Depositing User: | Umikalthom Abdullah |
| Date Deposited: | 19 Jun 2014 01:51 |
| Last Modified: | 24 Nov 2016 07:32 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1186/1752-153X-7-26 |
| URI: | http://psasir.upm.edu.my/id/eprint/30042 |
| Statistic Details: | View Download Statistic |
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