Synthesis of N-methoxy-N-methylaminocarbonyl-l, 4-benzoquinone: the First Quinone Carrying an N-methoxy-N-methylamino Group

Citation

Ahmad, Faujan (1988) Synthesis of N-methoxy-N-methylaminocarbonyl-l, 4-benzoquinone: the First Quinone Carrying an N-methoxy-N-methylamino Group. Pertanika, 11 (1). pp. 87-90.

Abstract

We report herein a four-step preparation of the title compound. Gentisic acid (1) was firstly converted into its diacetate (2) by treatment with acetic anhydride in the presence of concentrated sulfuric acid. Treatment of the diacetate with oxalyl chloride in dichloromethane in the presence of dimethylformamide followed by N-D-dimethyl-hydroxyamine hydrochloride and pyridine gave 2, 5-diacetoxy-Nmethoxy- N-methylbenzamide (3). Reaction of this with sodium hydrogen carbonate to generate the hydroquinone (4) followed by oxidation with silver oxide gave the desired quinone (5).

Download File

Preview

PDF
Synthesis_of_N-methoxy-N-methylaminocarbonyl-.pdf
Download (1MB)

Additional Metadata

Item Type:	Article
Divisions:	Faculty of Environmental Studies
Keywords:	Quinone synthesis N-methoxy-N-methylaminocarbonyl-l, 4-benzoquinone
Depositing User:	Nur Izyan Mohd Zaki
Date Deposited:	17 Nov 2009 01:55
Last Modified:	27 May 2013 07:02
URI:	http://psasir.upm.edu.my/id/eprint/2698
Statistic Details:	View Download Statistic

Actions (login required)

View Item