Citation
Nugroho, Agung Endro and Riyanto, Sugeng and Md.Sukari, Mohd. Aspollah and Maeyama, Kazutaka
(2011)
Effects of aegeline, a main alkaloid of aegle marmelos correa leaves, on the histamine release from mast cells.
Pakistan Journal of Pharmaceutical Sciences, 24 (3).
pp. 359-367.
ISSN 1011-601X
Abstract
Aegeline or N-[2-hydroxy-2(4-methoxyphenyl) ethyl]-3-phenyl-2-propenamide is a main alkaloid isolated from Aegle marmelos Correa collected in Yogyakarta Indonesia. In our study, we investigated the effects of aegeline on the histamine release from mast cell. The study was performed by using (1) rat basophilic leukemia (RBL-2H3) cell line, and (2) rat peritoneal mast cells (RPMCs). DNP24-BSA, thap pe of mast cell and also involved some mechanisms related to intracellular Ca 2+ signaling events via the same target of the action of thapsigargin or downstream process of intracellular Ca 2+ signaling in mast cells.
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Official URL or Download Paper: http://www.uok.edu.pk/faculties/pharmacy/
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Science |
| Publisher: | University of Karachi. Faculty of Pharmacy |
| Keywords: | Aegeline; Main Alkaloid of Aegle marmelos Correa leaves; Histamine release; Mast cell. |
| Depositing User: | Nur Farahin Ramli |
| Date Deposited: | 26 Aug 2013 02:00 |
| Last Modified: | 10 Dec 2015 03:44 |
| URI: | http://psasir.upm.edu.my/id/eprint/24883 |
| Statistic Details: | View Download Statistic |
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