UPM Institutional Repository

Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream.


Citation

Abdulkarim, Muthanna Fawzy and Abdullah, Ghassan Zuhair and Chitneni, Mallikarjun and M. Salman, Ibrahim and Ameer, Omar Ziad and Yam, Mun Fee and Mahdi, Elrashid Saleh and Sattar, Munavvar A. and Basri, Mahiran and M. Noor, Azmin (2010) Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. International Journal of Nanomedicine, 5. pp. 915-924. ISSN 1176-9114; ESSN:1178-2013

Abstract

During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but with the adverse effect of causing gastrointestinal ulcers. The present study investigated the in vitro and in vivo pharmacodynamic activity of a newly synthesized palm oil esters (POEs)-based nanocream containing piroxicam for topical delivery.


Download File

[img]
Preview
PDF (Abstract)
Topical piroxicam in vitro release and in vivo anti.pdf

Download (84kB) | Preview

Additional Metadata

Item Type: Article
Divisions: Faculty of Medicine and Health Science
Faculty of Science
DOI Number: https://doi.org/10.2147/IJN.S13305
Publisher: Dove Medical Press
Keywords: Piroxicam; Nanocream; Analgesic; Antiflammatory; Skin permeation.
Depositing User: Nur Farahin Ramli
Date Deposited: 12 Mar 2014 09:15
Last Modified: 05 Nov 2015 08:54
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2147/IJN.S13305
URI: http://psasir.upm.edu.my/id/eprint/24756
Statistic Details: View Download Statistic

Actions (login required)

View Item View Item