Citation
Abdulkarim, Muthanna Fawzy and Abdullah, Ghassan Zuhair and Chitneni, Mallikarjun and M. Salman, Ibrahim and Ameer, Omar Ziad and Yam, Mun Fee and Mahdi, Elrashid Saleh and Sattar, Munavvar A. and Basri, Mahiran and M. Noor, Azmin
(2010)
Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream.
International Journal of Nanomedicine, 5.
pp. 915-924.
ISSN 1176-9114; ESSN:1178-2013
Abstract
During recent years, there has been growing interest in use of topical vehicle systems to assist in drug permeation through the skin. Drugs of interest are usually those that are problematic when given orally, such as piroxicam, a highly effective anti-inflammatory, anti-pyretic, and analgesic, but with the adverse effect of causing gastrointestinal ulcers. The present study investigated the in vitro and in vivo pharmacodynamic activity of a newly synthesized palm oil esters (POEs)-based nanocream containing piroxicam for topical delivery.
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Additional Metadata
| Item Type: | Article |
|---|---|
| Divisions: | Faculty of Medicine and Health Science Faculty of Science |
| DOI Number: | https://doi.org/10.2147/IJN.S13305 |
| Publisher: | Dove Medical Press |
| Keywords: | Piroxicam; Nanocream; Analgesic; Antiflammatory; Skin permeation. |
| Depositing User: | Nur Farahin Ramli |
| Date Deposited: | 12 Mar 2014 09:15 |
| Last Modified: | 05 Nov 2015 08:54 |
| Altmetrics: | http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.2147/IJN.S13305 |
| URI: | http://psasir.upm.edu.my/id/eprint/24756 |
| Statistic Details: | View Download Statistic |
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