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Design, synthesis and antiviral potential of 14-aryl/heteroaryl-14H-dibenzo[a,j]xanthenes using an efficient polymer-supported catalyst.


Citation

Mohan Naidu, Kalla Reddi and Satheesh Krishna, Balam and Anil Kumar, Mungara and Arulselvan, Palanisamy and Khalivulla, Shaik Ibrahim and Olusegun, Lasekan (2012) Design, synthesis and antiviral potential of 14-aryl/heteroaryl-14H-dibenzo[a,j]xanthenes using an efficient polymer-supported catalyst. Molecules, 17 (6). pp. 7543-7555. ISSN 1420-3049; ESSN:1420-3049

Abstract

Polyethyleneglycol bound sulfonic acid (PEG-OSO₃H), a chlorosulphonic acid-modified polyethylene glycol was successfully used as an efficient and eco-friendly polymeric catalyst in the synthesis of 14-aryl/heteroaryl-14H-dibenzo[a,j]xanthenes obtained from the reaction of 2-naphthol and carbonyl compounds under solvent-free conditions with short reaction times and excellent yields. The biological properties of these synthesized title compounds revealed that compounds 3b, 3c, 3f and 3i showed highly significant anti-viral activity against tobacco mosaic virus.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Food Science and Technology
DOI Number: https://doi.org/10.3390/molecules1706754
Publisher: MDPI
Keywords: Aldehyde; 2-Naphthol; PEG-OSO3H; Neat reaction; Xanthenes; Tobacco mosaic virus.
Depositing User: Nur Farahin Ramli
Date Deposited: 08 Oct 2013 15:08
Last Modified: 09 Oct 2015 07:09
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.3390/molecules1706754
URI: http://psasir.upm.edu.my/id/eprint/24209
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