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Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid


Citation

Yap, Wei Boon and Tey, Beng Ti and Mohammed Alitheen, Noorjahan Banu and Tan, Wen Siang (2012) Display of the antigenic region of Nipah virus nucleocapsid protein on hepatitis B virus capsid. Journal of Bioscience and Bioengineering, 113 (1). pp. 26-29. ISSN 1389-1723; ESSN: 1347-4421

Abstract

The C-terminal domain of Nipah virus (NiV) nucleocapsid protein (NP 401-532) was inserted at the N-terminus and the immunodominant loop of hepatitis B core antigen (HBc). The stability of NP 401-532 increased tremendously when displayed on the HBc particles. These particles reacted specifically with the swine anti-NiV and the human anti-HBc antisera.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Faculty of Engineering
Institute of Bioscience
DOI Number: https://doi.org/10.1016/j.jbiosc.2011.09.007
Publisher: The Society for Biotechnology, Japan
Keywords: Nipah virus; Nucleocapsid protein; Hepatitis B virus; Hepatitis B core antigen; Virus-like particles
Depositing User: Nur Farahin Ramli
Date Deposited: 10 Oct 2013 03:00
Last Modified: 30 Nov 2016 07:57
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1016/j.jbiosc.2011.09.007
URI: http://psasir.upm.edu.my/id/eprint/24187
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