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Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).


Citation

Chong, Hueh Zan and Rahmat, Asmah and Md. Akim, Abdah and Mohamed Alitheen, Noorjahan Banu and Othman, Fauziah and Cheng, Gwendoline Lian Ee (2011) Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa). Nutrition and Food Science, 41 (4). pp. 238-241. ISSN 0034-6659

Abstract

Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts(0-100mg/ml) using 72-h MTT assay. Findings – Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma),HT-29 (colon carcinoma), MDA-MB-231 (non-hormone-dependent breast cancer), MCF-7(hormone-dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC50) were obtained for MDA-MB-231, HepG2, HT-29. Extracts within the concentrations of 10-100mg/ml were found not to be effective against proliferation of MCF-7 and HeLa.


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Additional Metadata

Item Type: Article
Divisions: Faculty of Biotechnology and Biomolecular Sciences
Faculty of Medicine and Health Science
Faculty of Science
DOI Number: https://doi.org/10.1108/00346651111151366
Publisher: Emerald Group Publishing
Keywords: Curcuma longa; Cytology; Cytotoxic effect; Etlingera elatior; Malaysia; MTT assay; Pandanus amaryllifolius; Plants.
Depositing User: Nur Farahin Ramli
Date Deposited: 24 Feb 2014 02:30
Last Modified: 05 Oct 2015 09:19
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1108/00346651111151366
URI: http://psasir.upm.edu.my/id/eprint/24087
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