Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure

Citation

Hamzah, Hazilawati and P., Farah Dina and Shaari, Mohd Rosly and Sithambaram, Shanmugavelu and Mohamed Mustapha, Noordin (2010) Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure. Medical Journal of Malaysia, 65 (suppl.B). pp. 132-134. ISSN 0300-5283

Abstract

Phyllanthus niruri is commonly used for treatment of jaundice, hepatitis, kidney stones, diuretics, influenza and antibacterial agent. This study was conducted to investigate the effects of P. niruri in reducing the severity of azotaemia in rats induced with chronic renal damage. A total of 32 male Sprague Dawley rats were randomly assigned into four treatment groups; Group A (control), Group B (adenine), Group C (P. niruri) and Group D (adenine+P. niruri), consisting of 8 rats each. Chronic renal damage was induced using 0.75% adenine mixed with rat diet (daily feeding for 6 weeks). P. niruri was supplemented daily at a dose of 3000 mg/kg body weight throughout the 10 weeks of the experimental period. Results showed that P. niruri reduced the severity of azotaemia in rats induced with chronic renal damage.

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Official URL or Download Paper: http://www.e-mjm.org/2010/Sup_tissue_engineering_c...

Additional Metadata

Item Type:	Article
Divisions:	Faculty of Veterinary Medicine
Publisher:	Malaysian Medical Association
Notes:	Poster presented at 3rd Malaysian Tissue Engineering and Regenerative Medicine Scientific Meeting 2010
Keywords:	Phyllanthus niruri; Azotaemia; Rats; Chronic renal damage
Depositing User:	Azizan Arshad
Date Deposited:	20 Nov 2013 00:31
Last Modified:	21 Nov 2016 08:52
URI:	http://psasir.upm.edu.my/id/eprint/16189
Statistic Details:	View Download Statistic

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