Citation
Khairul Ikram, Emmy Hainida and Ismail, Amin and Hashim, Normah and Mohd Esa, Norhaizan and Abu Bakar, Ainul Zakiah
(2008)
Effects of defatted dried roselle (Hibiscus sabdariffa L.) seed powder on lipid profiles of hypercholesterolemia rats.
Journal of the Science of Food and Agriculture, 88 (6).
pp. 1043-1050.
ISSN 0022-5142; ESSN: 1097-0010
Abstract
BACKGROUND: In vivo investigations were made of the effect of defatted dried roselle seed powder (DRS) on the lipid profiles of rats with induced hypercholesterolemia. The two-batch sample consisted of 23 and 20 Sprague-Dawley male rats randomly divided into four groups and fed with four different diets. The first batch of rats was fed with normal, hypercholesterol, hypercholesterol + 10 g kg-1 (w/w) DRS and hypercholesterol + 20 g kg-1 (w/w) DRS diets. The second batch of rats was fed with normal, hypercholesterol, hypercholesterol + 50 g kg-1 (w/w) DRS and hypercholesterol + 150 g kg-1 (w/w) DRS diets. Treatments were given for a total of 5 weeks.
RESULTS: Results indicated that the addition of 10 g kg-1 and 20 g kg-1 of DRS did not significantly lower the plasma total cholesterol (TC) levels. In contrast, 50 g kg-1 and 150 g kg-1 DRS significantly lowered (P < 0.05) the TC and low density lipoprotein cholesterol (LDL-C) levels.
CONCLUSION: The addition of 50 g kg-1 and 150 g kg-1 DRS showed potential hypocholesterolemic effects. Furthermore, these findings indicated that protein, lipid and dietary fibre were high in the seed powder.
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