Citation
Abd Hamid @ Abdul Razak, Roslida and A. K., Erazuliana and Ahmad, Zuraini
(2008)
Anti-inflammatory and antinociceptive activities of the ethanolic extract of Pluchea indica (L) less leaf.
Pharmacologyonline, 2.
pp. 349-360.
ISSN 1827-8620
Abstract
Ethanolic extract of Pluchea indica leaf (PIL) was used to investigate its anti-inflammatory and antinociceptive activities by using carrageenan - induced oedema model and acetic acid induced writhing test. PIL exhibited significant and dose-dependent anti-inflammatory activity at a dose of 300 mg/kg when administered orally. It is also demonstrated that the i.p administration of PIL at a dose of 10, 30, 100 and 300 mg/kg produced significant inhibition of abdominal constriction induced with 0.6% (v/v) acetic acid in dose dependent manner. These results indicate that PIL exhibits significant anti-inflammatory and antinociceptive effects.
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Additional Metadata
Item Type: | Article |
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Divisions: | Faculty of Medicine and Health Science |
Publisher: | Società Italo-Latinoamericana di Etnomedicina |
Keywords: | Acetic acid induced writhing; Carrageenan-induced oedema; Pluchea indica |
Depositing User: | Nabilah Mustapa |
Date Deposited: | 26 Jan 2016 02:17 |
Last Modified: | 31 Oct 2016 01:53 |
URI: | http://psasir.upm.edu.my/id/eprint/13149 |
Statistic Details: | View Download Statistic |
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