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Alkaloids from Piper sarmentosum and Piper nigrum


Ee, Gwendoline Cheng Lian and Lim, Chyi Meei and Lim, Chan Kiang and Rahmani, Mawardi and Shaari, Khozirah and Bong, Joseph Choon Fah (2009) Alkaloids from Piper sarmentosum and Piper nigrum. Natural Product Research, 23 (15). pp. 1416-1423. ISSN 1478-6419; ESSN: 1029–2349


Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4' (methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques. Cytotoxic activity screening of the plant extracts indicated some activity.

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Additional Metadata

Item Type: Article
Divisions: Faculty of Science
DOI Number: https://doi.org/10.1080/14786410902757998
Publisher: Taylor & Francis
Keywords: Piper nigrum; Piper sarmentosum; Alkaloids; Cytotoxic
Depositing User: Nurul Ainie Mokhtar
Date Deposited: 06 Jun 2015 07:56
Last Modified: 14 Sep 2015 02:47
Altmetrics: http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1080/14786410902757998
URI: http://psasir.upm.edu.my/id/eprint/12986
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