Citation
Ee, Gwendoline Cheng Lian and Lim, Chyi Meei and Lim, Chan Kiang and Rahmani, Mawardi and Shaari, Khozirah and Bong, Joseph Choon Fah
(2009)
Alkaloids from Piper sarmentosum and Piper nigrum.
Natural Product Research, 23 (15).
pp. 1416-1423.
ISSN 1478-6419; ESSN: 1029–2349
Abstract
Detailed chemical studies on the roots of Piper sarmentosum and Piper nigrum have resulted in several alkaloids. The roots of P. sarmentosum gave a new aromatic compound, 1-nitrosoimino-2,4,5-trimethoxybenzene (1). Piper nigrum roots gave pellitorine (2), (E)-1-[3',4' (methylenedioxy)cinnamoyl]piperidine (3), 2,4-tetradecadienoic acid isobutyl amide (4), piperine (5), sylvamide (6), cepharadione A (7), piperolactam D (8) and paprazine (9). Structural elucidation of these compounds was achieved through NMR and MS techniques. Cytotoxic activity screening of the plant extracts indicated some activity.
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