Towards a core outcome set for sarcopenia intervention studies: a scoping review identifying the most frequently reported outcomes across randomized controlled trials in sarcopenia

Citation

Van Heden, S. and Chan, Y. M. and Baoubbou, Z. and Bruyère, O. and Reginster, J. Y. and Surquin, M. and Sanchez-Rodriguez, D. and Beaudart, C. (2025) Towards a core outcome set for sarcopenia intervention studies: a scoping review identifying the most frequently reported outcomes across randomized controlled trials in sarcopenia. European Geriatric Medicine, 16 (6). pp. 2033-2045. ISSN 1878-7649; eISSN: 1878-7657

Abstract

Aim: As a first step in the development of a Core Outcome Set, we carried out a scoping review using a systematic methodology to identify the most frequently reported outcomes in sarcopenia intervention studies. Findings: This scoping review identified 253 distinct outcomes, revealing a high degree of heterogeneity across clinical trials. Muscle mass, muscle strength, and physical performance are the most frequently reported outcomes in sarcopenia trials. Message: A considerable diversity and heterogeneity of reported outcomes were observed in clinical trials, highlighting the urgent need for outcome standardization and the development of a Core Outcome Set specifically for sarcopenia interventions.

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Additional Metadata

Item Type:	Article
Subject:	Gerontology
Subject:	Geriatrics and Gerontology
Divisions:	Faculty of Medicine and Health Science Malaysian Research Institute on Ageing
DOI Number:	https://doi.org/10.1007/s41999-025-01285-x
Publisher:	Springer Science and Business Media Deutschland GmbH
Keywords:	Core outcome set—outcomes; Interventional; Older people; Sarcopenia; Scoping review
Depositing User:	Ms. Zaimah Saiful Yazan
Date Deposited:	14 Jan 2026 04:46
Last Modified:	14 Jan 2026 04:46
Altmetrics:	http://www.altmetric.com/details.php?domain=psasir.upm.edu.my&doi=10.1007/s41999-025-01285-x
URI:	http://psasir.upm.edu.my/id/eprint/122346
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